It happened just before 1 pm on Broadway at 29th Street.
Authorities say the cab was westbound on 29th Street turning left onto Broadway when the driver collided with a CitiBike at the intersection.
The driver then careened onto the sidewalk, mowing down several pedestrians and pinning two women underneath the vehicle.
In what NYPD Deputy Police Chief John Chell called a “remarkable scene,” between 15 and 20 good Samaritans tried to lift the cab off the victims.
Three people were transported in critical condition to Bellevue, and two others had non-life threatening injuries, according to the FDNY.
The cab driver, who remained at the scene, also had non-life-threatening injuries.
It is unclear if he may have experienced a medical condition, and the investigation is ongoing.
At this time, authorities believe it to be accidental and not criminal in nature.
ALSO READ | Three members of the same family killed in Queens fire
* Get Eyewitness News Delivered
* More Manhattan news
* Send us a news tip
* Download the abc7NY app for breaking news alerts
* Follow us on YouTube
Submit a tip or story idea to Eyewitness News
Copyright © 2022 WABC-TV. All Rights Reserved.